Michigan State vs.
Michigan State · ToledoA new era begins for both programs, with new head coaches leading the way. Toledo also enters a new era under Mike Jacobs after Jason Candle left to become the head coach at UConn.
Jacobs has won everywhere he's been, compiling a 94-23 career record as a head coach. Now, he'll bring that success to the MAC and look to keep the Rockets among the conference's top programs.
However, with a new coaching staff and a heavily revamped roster, Toledo could experience some early growing pains against a Big Ten opponent. Let’s take a look at the odds for Michigan State vs. Toledo at FanDuel Sportsbook as of Sept. 4.
This page may contain affiliate links to legal sports betting partners. From tailgating to fan fest to official kickoff time -- here's your game day guide for Michigan State football's season-opener vs. Toledo today
KEY POINTS
- Michigan State vs. Toledo Prediction, Odds, Picks for College Football Week 1.
- The Michigan State Spartans will kick off their 2026 college football season against the Toledo Rockets at Spartan Stadium on Friday in a Week 1 matchup on FS1.
- The Spartans hired Pat Fitzgerald to turn around a program that reached the four-team College Football Playoff in 2015 but hasn't posted a winning season since 2021.
- The Spartans will open the 2026 season on Friday in a home game from Spartan Stadium against the Toledo Rockets of the Mid-American Conference.